Apostolos Georgopoulos, MD, PhD
Education
Regents Professor
McKnight Presidential Chair in Cognitive Neuroscience, Department of Neuroscience
Director and American Legion Brain Sciences Chair, Brain Sciences Center
Faculty, Graduate Program in Neuroscience
Professor of Neuroscience, Neurology, and Psychiatry
Affiliate Faculty, Institute for Health Informatics (IHI)
Affiliate Faculty, Center for Cognitive Sciences
MD, University of Athens School of Medicine
Ph.D. degree in Physiology, University of Athens, Greece, 1969
Research
Research Summary/Interests
Brain Mechanisms of Movement and Cognition; Functional Brain Biomarkers; Cortical Networks
There three major goals of our research: First, to elucidate the neural mechanisms underlying motor control and cognitive processing; second, to develop functional brain biomarkers for various brain diseases; and third, to understand the workings of developing cortical networks. For the first aim, we pursue experimental psychological studies, neurophysiological recordings, functional magnetic resonance imaging (MRI) at high fields (3, 4 and 7 Tesla), magnetoencephalography (MEG), and neural network modeling (using a supercomputer). For the second aim, we use MEG. And for the third aim, we record electrical activity from embryonic cortical cell cultures using multielectrode arrays.
- Magnetoencephalography of brain function
- Neural mechanisms of cognitive processes
- Neurophysiology of motor control and cognition
- Functional MRI of motor and cognitive processes
Publications
James, LM & Georgopoulos, AP 2019, 'Human leukocyte antigen as a key factor in preventing dementia and associated apolipoprotein E4 risk', Frontiers in Aging Neuroscience, vol. 11, no. APR, 82. https://doi.org/10.3389/fnagi.2019.00082
James LA, Engdahl BE, Johnson RA & Georgopoulos AP 2019, ‘Gulf War Illness and Inflammation: Association of symptom severity with C-reactive protein’ J Neurol Neuromed vol. 4, no. 2, pp. 15-19. https://doi.org/10.29245/2572.942X/2019/2.1245
James, LM, Dolan, S, Leuthold, AC, Engdahl, BE, Georgopoulos, A & Georgopoulos, AP 2018, 'The effects of human leukocyte antigen DRB1*13 and apolipoprotein E on age-related variability of synchronous neural interactions in healthy women', EBioMedicine, vol. 35, pp. 288-294. https://doi.org/10.1016/j.ebiom.2018.08.026
Charonis, S, James, LM, Georgopoulos AP 2019, ‘In silico Analysis of the Binding Affinities of Antigenic Epitopes of Vaccines Administered to Gulf War Veterans to Specific HLA Class II Alleles Protective for Gulf War Illness’ J Neurol Neuromed, vol. 4, no. 5, pp. 23-30. https://doi.org/10.29245/2572.942X/2019/5.1257
Tsilibary, EP, Souto, EP, Kratzke, M, James, LM, Engdahl, BE & Georgopoulos AP 2019, ‘Anthrax and Gulf War Illness (GWI): Evidence for the Presence of Harmful Anthrax Antigen PA63 In the Serum of Veterans with GWI’ J Neurol Neuromed, vol. 4, no. 6, pp. 1-9. https://doi.org/10.29245/2572.942X/2019/6.1255
Christova, P & Georgopoulos, AP 2018, 'Invariant and heritable local cortical organization as revealed by fMRI' Journal of neurophysiology, vol. 120, no. 2, pp. 760-764. https://doi.org/10.1152/jn.00137.2018
Carpenter, A, Baud-Bovy, G, Georgopoulos, AP & Pellizzer, G 2018, 'Encoding of serial order in working memory: Neuronal activity in motor, premotor, and prefrontal cortex during a memory scanning task' Journal of Neuroscience, vol. 38, no. 21, pp. 4912-4933. https://doi.org/10.1523/JNEUROSCI.3294-17.2018
James, LM, Dolan, S, Leuthold, AC, Engdahl, B, Georgopoulos, A & Georgopoulos, AP 2018, 'The effects of human leukocyte antigen DRB1*13 and apolipoprotein E on age-related variability of synchronous neural interactions in healthy women' EBioMedicine, vol. 35, pp. 288-294. https://doi.org/10.1016/j.ebiom.2018.08.026
James, LM, Christova, P, Lewis, SM, Engdahl, B, Georgopoulos, A & Georgopoulos, AP 2018, 'Protective Effect of Human Leukocyte Antigen (HLA) Allele DRB1*13:02 on Age-Related Brain Gray Matter Volume Reduction in Healthy Women' EBioMedicine, vol. 29, pp. 31-37. https://doi.org/10.1016/j.ebiom.2018.02.005
Georgopoulos, AP & Georgopoulos, A 2017, 'The Beautiful Brain and the influence of Santiago Ramón y Cajal on medicine' JAMA - Journal of the American Medical Association, vol. 318, no. 6, pp. 502-504. https://doi.org/10.1001/jama.2017.9858